Episode 5: Rebellion of the Cells - Cancer and the Immune System
Timecode list

Timecode 00:25 - 04:34

Tumor tissue

What is cancer?

Cancer is a result of genetic changes in the cells, which can also be a consequence of external influences. Some types of cancer cells are able to deactivate the cell death program which normally ensures that cells die when they are no longer needed by the organism.


Timecode 04:35 - 06:33

Killer cells attack cancer cells

Cancer and the immune system

If cancer cells display features which mark them as being foreign objects, these deviate cells are tracked down and eliminated by the immune system. But if these features are missing, the cancer cells can divide without restraint.

Start animated film
(Length: 1:30 min)


Timecode 06:34 - 10:10

Leukaemia treatment

Blood cancer - leukaemia

Leukaemia is a malignant change in the white blood cells. The pathological cells can be destroyed by chemotherapy and radiation. The lack of vital white blood cells can be compensated by the transplant of cells which create blood, e.g., from the bone marrow.


Timecode 10:01 - 12:36

"Miracle weapon"

Hope for new cancer therapies

Publications in the media which speak of a miracle weapon against cancer awaken hopes for cancer patients which generally prove illusory.


Timecode 12:36 - 16:49

Apoptosis

Immune therapy for cancer

More recent immune-therapeutic approaches attempt to improve the recognition of cancer cells so that they can be specifically destroyed.

Start animated film 1
(Length: 0:40 min)
Start animated film 2
(Length: 1:00 min)


Timecode 16:50 - 22:17

Antibody production

Vaccination for cancer

One method for fighting cancer cells consists of producing antibodies. They are supposed to attach themselves to cancer cells and initiate their destruction.

Start animated film
(Length: 1:40 min)


Timecode 22:18 - 27:16

Risk factor smoking

Cancer prevention

If people avoid carcinogenic risks and keeps themselves in good physical condition, they can prevent an illness. Sports also help cancer patients to deal better physically and psychologically with their illness.

 

Content

The programme describes how difficult it is for the immune system to recognize and eliminate cancer cells.

Cancer arises from the pathological changes in the genetic material of the cell. Karl Heinrich Bauer, the founder of the German Cancer Research Centre, discovered this. Cancer cells also appear in healthy bodies, but they are normally eliminated by the immune system. This prevents the illness from taking hold in the body. Unfortunately, the elimination of the cancer cells is not always successful. There are several reasons for this.

Some cancer cells are able to deactivate the cell death program (apoptosis) and, in this way, protect themselves from the attacks of the immune system.

Cancer cells, which are a form of healthy cells, cannot always be recognized as foreign bodies, taking themselves out of the sights of the immune defences. The immune system is weakened and can no longer prevent the formation of tumours.

One type of cancer, leukaemia, is discussed in greater detail. In the course of the disease, the blood cells multiply without restraint and are damaged. But many patients can be helped with bone marrow transplants and chemotherapy.

More recent research is aimed at adding new weapons to the immune system's arsenal or making cancer cells easier to recognize. Some of the approaches in this direction are described and visualized using animated films.

Types of sports which increase endurance reinforce the body's defences, reduce stress and consequently reduce the risk of cancer.